Solving cancer from first principles.

Galen is an autonomous AI that does causal cancer research 24 hours a day — tracing mechanisms, generating hypotheses, and grounding every claim in experimental evidence.What we’re building toward is cancer superintelligence — and making it available to every patient, clinician, and researcher who needs it.

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Autonomous Research

Every cancer is different. Finding information isn’t the hard part — reasoning about it is.

More than 5,000 cancer studies are published every week. But the challenge facing patients and clinicians isn’t finding this information — it’s integrating across dimensions that don’t naturally connect. A patient’s tumor isn’t defined by one mutation, one pathway, or one treatment. It’s shaped by the causal interactions between all of them — interactions that evolve as resistance develops, as new drugs are introduced, and as the tumor adapts. That demands more than search. It demands reasoning that traces causes, models interventions, and anticipates what happens next.

An intelligence that reads everything, forgets nothing, and never stops.

Galen continuously integrates experimental evidence from the world’s biomedical databases — genomic studies, clinical trials, drug mechanisms — into a causal reasoning engine. Most AI finds correlations in data. Galen traces the mechanisms underneath — why a mutation drives resistance, why a treatment works, and why it might stop working.

Mutation identified
EGFR L858R
Pathway traced
MAPK signaling
Treatment matched
Osimertinib

Most AI in cancer works at the first level — association. Drug X is associated with mutation Y. That’s a lookup table, not an understanding.

Galen reasons at three levels. Association: osimertinib is commonly used for EGFR L858R. Intervention: inhibiting EGFR suppresses downstream MAPK signaling, slowing tumor growth. Counterfactual: if this patient carried a different mutation — say, C797S — a different mechanism of resistance would emerge, demanding a different therapeutic strategy.

The difference matters most when the evidence is thin — rare mutations, unusual combinations, newly approved therapies where historical data doesn’t exist yet. That’s where pattern-matching breaks down and causal reasoning becomes essential.

See how Galen reasons.

Every answer traces back to its source. Choose a question and see the evidence chain.

app.usegalen.com

Choose a question:

Causes, not correlations.

Galen maintains a structural causal model of cancer biology. It doesn’t just report that a drug works — it traces why: from mutation, to mechanism, to treatment, to resistance. That causal chain is what allows Galen to reason about cases it has never seen before.

1

Association “Drug X works for mutation Y.”

2

Intervention “Inhibiting target Z suppresses this pathway.”

3

Counterfactual “A different mutation would change the strategy.”

Privacy by design.

Built with care for sensitive health data. Your questions are yours.

Built by people who understand cancer.

Physicians, engineers, and researchers — not a general-purpose AI team chasing healthcare as a vertical.

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Start with what matters to you.

Whether you’re navigating a diagnosis, preparing for a case, or building something new — Galen is ready.